If you work at love, you will find love at work.

I think that's the job of a director really, to sort of funnel all the creativity into one centralized point of being.

I was bullied and regarded as little bit of an oddball myself.

What I don't like are pompous, pretentious movies.

I want to make movies just like "King Kong." You know, dinosaurs, big gorillas - it's everything that a nine year-old boy would fall in love with.

Filmmaking for me is always aiming for the imaginary movie and never achieving it.

I find that in the process of making a film you're constantly discovering things that you never even imagined would work at the beginning.

I think there's still a little bit of that 9 year-old in me and I'm pretty happy.

Remember, pain is temporary; film is forever.

Defeat is always momentary.

The most honest form of filmmaking is to make a film for yourself.

Now I won't have to worry about the new series making it or not.

Less than 1 percent of the patients treated are alive at the end of five years.

Boy, you gotta be real sick to get this much attention.

I don't mind dying if I have to, but I'm damned if I want to pay for the guarantee. I'm sorry.

With a houseful of kids you give each other strength.

You can die of the cure before you die of the illness.

I've had a good life. Enough happiness, enough success.

I'm not the kind of person who gives up without a fight.